Pub. Date : 2000 Jun
PMID : 10820139
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mean activities of microsomal CYP1A2, CYP2B6, and CYP3A4/5 from modafinil-treated hepatocytes were higher (up to 2-fold) than those in the solvent-treated controls but were less than those produced by reference inducers of these enzymes. | Modafinil | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | Overall, modafinil was shown to have effects on human hepatic CYP1A2, CYP2B6, CYP2C9, CYP2C19, and CYP3A4/5 activities in vitro. | Modafinil | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |