Title : Calcium regulation of gelsolin and adseverin: a natural test of the helix latch hypothesis.

Pub. Date : 2000 May 9

PMID : 10819996






7 Functional Relationships(s)
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1 Calcium regulation of gelsolin and adseverin: a natural test of the helix latch hypothesis. Calcium gelsolin Homo sapiens
2 This helix has been postulated to serve as a calcium-sensitive latch, keeping gelsolin inactive. Calcium gelsolin Homo sapiens
3 We find that the relationship between severing rate and calcium ion concentration differs between gelsolin and adseverin, and suggest that calcium controls one rate-limiting step in the activation of adseverin and two in the activation of gelsolin. Calcium gelsolin Homo sapiens
4 We find that the relationship between severing rate and calcium ion concentration differs between gelsolin and adseverin, and suggest that calcium controls one rate-limiting step in the activation of adseverin and two in the activation of gelsolin. Calcium gelsolin Homo sapiens
5 We find that the relationship between severing rate and calcium ion concentration differs between gelsolin and adseverin, and suggest that calcium controls one rate-limiting step in the activation of adseverin and two in the activation of gelsolin. Calcium gelsolin Homo sapiens
6 We find that the relationship between severing rate and calcium ion concentration differs between gelsolin and adseverin, and suggest that calcium controls one rate-limiting step in the activation of adseverin and two in the activation of gelsolin. Calcium gelsolin Homo sapiens
7 These results support the C-terminal latch hypothesis for the calcium ion activation of gelsolin. Calcium gelsolin Homo sapiens