Title : Antidepressant drug administration modifies the interactive relationship between alpha(2)-adrenergic sensitivity and levels of TNF in the rat brain.

Pub. Date : 2000 Jul 10

PMID : 10808050






2 Functional Relationships(s)
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1 Chronic (14 days) administration of the antidepressant drugs desipramine or zimelidine transforms alpha(2)-adrenergic receptor-dependent decreases in TNF levels to increases in levels of TNF in the locus coeruleus. Desipramine tumor necrosis factor Rattus norvegicus
2 Chronic (14 days) administration of the antidepressant drugs desipramine or zimelidine transforms alpha(2)-adrenergic receptor-dependent decreases in TNF levels to increases in levels of TNF in the locus coeruleus. Desipramine tumor necrosis factor Rattus norvegicus