Title : Assignment of functional amino acids around the active site of human DNA topoisomerase IIalpha.

Pub. Date : 2000 Aug 11

PMID : 10807924






1 Functional Relationships(s)
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1 An expression library for active site mutants of human topoisomerase IIalpha (TOP2alpha) was constructed by replacing the sequence encoding residues 793-808 with a randomized oligonucleotide cassette. Oligonucleotides DNA topoisomerase II alpha Homo sapiens