Title : Limiting numbers of G156A O(6)-methylguanine-DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection.

Pub. Date : 2000 May 15

PMID : 10807772






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 We selected for G156A MGMT (triangle upMGMT) transduced LTRC present in 5 x 10(4) to 100 x 10(4) marrow cells infused into nonmyeloablated mice by the administration of O(6)-benzylguanine (BG) and BCNU every 3 to 4 weeks. Carmustine O-6-methylguanine-DNA methyltransferase Mus musculus