Pub. Date : 1999 May 1
PMID : 10796078
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Positive regulation of the rat CYP2B2 phenobarbital response unit by the nuclear receptor hexamer half-site.nuclear factor 1 complex. | Phenobarbital | cytochrome P450, family 2, subfamily b, polypeptide 2 | Rattus norvegicus |
| 2 | A distal 163-bp fragment mediates phenobarbital responsiveness of the rat CYP2B2 gene. | Phenobarbital | cytochrome P450, family 2, subfamily b, polypeptide 2 | Rattus norvegicus |
| 3 | We introduced into the rat CYP2B2 hexamer half-site the specific mutational change previously introduced into the Cyp2b10 sequence, where its effect was to increase the basal level of expression and to abolish phenobarbital responsiveness. | Phenobarbital | cytochrome P450, family 2, subfamily b, polypeptide 2 | Rattus norvegicus |