Title : New proline mimetics: synthesis of thrombin inhibitors incorporating cyclopentane- and cyclopentenedicarboxylic acid templates in the P2 position. Binding conformation investigated by X-ray crystallography.

Pub. Date : 2000 May 4

PMID : 10794688






1 Functional Relationships(s)
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1 New proline mimetics: synthesis of thrombin inhibitors incorporating cyclopentane- and cyclopentenedicarboxylic acid templates in the P2 position. Cyclopentanes coagulation factor II, thrombin Homo sapiens