Title : Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed.

Pub. Date : 2000 May

PMID : 10785598






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Exposure to 5-FU (50 and 100 microM) and ZD1694 (50 and 100 nM) for 24 and 48 h induced p53 and p21 expression in wt p53 cells, but not in mt p53 cells. Fluorouracil H3 histone pseudogene 16 Homo sapiens