Title : Cyclooxygenase-2 is required for tumor necrosis factor-alpha- and angiotensin II-mediated proliferation of vascular smooth muscle cells.

Pub. Date : 2000 Apr 28

PMID : 10785514






1 Functional Relationships(s)
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1 The COX-2-selective inhibitors NS-398 and nimesulide and the TXA(2) receptor antagonist BMS 180,291 inhibited TNF-alpha- and Ang II-mediated increases in DNA content and cell number by approximately 95%. N-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide tumor necrosis factor Homo sapiens