Pub. Date : 2000 Jul 7
PMID : 10777476
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Mechanism of reaction of myeloperoxidase with nitrite. | Nitrites | myeloperoxidase | Homo sapiens |
2 | In order to clarify if nitrite could be a physiological substrate of myeloperoxidase, we investigated the reactions of the ferric enzyme and its redox intermediates, compound I and compound II, with nitrite under pre-steady state conditions by using sequential mixing stopped-flow analysis in the pH range 4-8. | Nitrites | myeloperoxidase | Homo sapiens |
3 | In order to clarify if nitrite could be a physiological substrate of myeloperoxidase, we investigated the reactions of the ferric enzyme and its redox intermediates, compound I and compound II, with nitrite under pre-steady state conditions by using sequential mixing stopped-flow analysis in the pH range 4-8. | Nitrites | myeloperoxidase | Homo sapiens |
4 | At 15 degrees C the rate of formation of the low spin MPO-nitrite complex is (2.5 +/- 0.2) x 10(4) m(-1) s(-1) at pH 7 and (2.2 +/- 0.7) x 10(6) m(-1) s(-1) at pH 5. | Nitrites | myeloperoxidase | Homo sapiens |
5 | Nitrite is oxidized by two one-electron steps in the MPO peroxidase cycle. | Nitrites | myeloperoxidase | Homo sapiens |