Title : Carbamazepine--indinavir interaction causes antiretroviral therapy failure.

Pub. Date : 2000 Apr

PMID : 10772431






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Carbamazepine is a potent enzyme inducer, predominantly of the CYP3A enzyme system, while HIV-protease inhibitors such as indinavir are substrates for and inhibitors of CYP3A. Carbamazepine cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Carbamazepine is a potent enzyme inducer, predominantly of the CYP3A enzyme system, while HIV-protease inhibitors such as indinavir are substrates for and inhibitors of CYP3A. Carbamazepine cytochrome P450 family 3 subfamily A member 4 Homo sapiens