Title : Inhibition of cytokine secretion from human leukemic mast cells and basophils by H1- and H2-receptor antagonists.

Pub. Date : 2000 Apr

PMID : 10772385






2 Functional Relationships(s)
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1 In order to confirm and expand these studies, we have compared several H1-blockers and the H2-blocker ranitidine for their effect on TNF-alpha, IL-3, 6, 8 and GM-CSF release from human leukemic mast (HMC-1) and basophilic (KU812) cells, compared to dexamethasone. Ranitidine interleukin 3 Homo sapiens
2 Dexamethasone inhibited all cytokines, but ranitidine only TNF-alpha and IL-3. Ranitidine interleukin 3 Homo sapiens