Title : Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism.

Pub. Date : 2000 Apr 14

PMID : 10771285






1 Functional Relationships(s)
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1 Our results showed that CYP3A4/5 contributes to testosterone 6beta-hydroxylation, taxol phenol formation, diazepam 3-hydroxylation, diazepam N-demethylation, and aflatoxin B1 3-hydroxylation in human liver by 79.2%, 81.5%, 73. testosterone 6beta cytochrome P450 family 3 subfamily A member 4 Homo sapiens