Title : Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism.

Pub. Date : 2000 Apr 14

PMID : 10771285






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CYP2E1 contributes to chlorzoxazone 6-hydroxylation, p-nitroanisole O-demethylation, and toluene hydroxylation by 45.8%, 27.7% and 44.2% respectively, and CYP2C8/9/19 contribute to diazepam N-demethylation by 30.6%. Toluene cytochrome P450 family 2 subfamily E member 1 Homo sapiens