Title : Expression of dioxin-related transactivating factors and target genes in human eutopic endometrial and endometriotic tissues.

Pub. Date : 2000 Apr

PMID : 10764452






2 Functional Relationships(s)
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1 To understand the potential underlying molecular mechanisms we studied the expressions of cytochrome P-450 genes (CYP1A1, CYP1A2, and CYP1B1 ), which are induced by dioxin, and the expressions of cytosolic receptor for dioxin, aryl hydrocarbon receptor, and its nuclear translocator, aryl hydrocarbon receptor nuclear translocator protein, in endometriotic and eutopic endometrial tissues. Dioxins cytochrome P450 family 1 subfamily B member 1 Homo sapiens
2 CONCLUSION: We demonstrated for the first time the expression of dioxin-related transcription factors aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator protein and target genes CYP1A1, CYP1A2, and CYP1B1 in endometriotic tissues and stromal cells. Dioxins cytochrome P450 family 1 subfamily B member 1 Homo sapiens