Pub. Date : 2000 Apr
PMID : 10759183
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Interferon-gamma modulates human oligodendrocyte susceptibility to Fas-mediated apoptosis. | ammonium ferrous sulfate | interferon gamma | Homo sapiens |
| 2 | Furthermore, IFN-gamma-treated OLs became susceptible to Fas-mediated apoptosis when compared with untreated cells, and were protected by pretreatment with the caspase inhibitor ZVAD. | ammonium ferrous sulfate | interferon gamma | Homo sapiens |
| 3 | Our results thus indicate that IFN-gamma is not directly cytotoxic for human OLs in culture, but could indirectly modulate functional injury-related responses by upregulating Fas on the cell surface. | ammonium ferrous sulfate | interferon gamma | Homo sapiens |