Title : Stimulation by eicosapentaenoic acids of leptin mRNA expression and its secretion in mouse 3T3-L1 adipocytes in vitro.

Pub. Date : 2000 Apr 13

PMID : 10753628






2 Functional Relationships(s)
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1 On the other hand, inhibition by 6-diazo-5-oxo-l-norleucine of the rate-limiting enzyme in hexosamine biosynthesis blunted EPA-induced stimulation of leptin mRNA expression and its secretion. Hexosamines leptin Mus musculus
2 These data suggest that EPA up-regulates leptin gene expression and its secretion probably through a hexosamine biosynthetic pathway. Hexosamines leptin Mus musculus