Title : Effect of troglitazone on cytochrome P450 enzymes in primary cultures of human and rat hepatocytes.

Pub. Date : 2000 Mar

PMID : 10752642






1 Functional Relationships(s)
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1 During clinical investigations of drug-drug interactions with therapeutics (terfenadine and cyclosporine) known to be metabolized by CYP3A4, pharmacokinetic interactions were noted upon troglitazone multiple-dose treatments. Cyclosporine cytochrome P450 family 3 subfamily A member 4 Homo sapiens