Pub. Date : 2000 Jun 1
PMID : 10751543
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | This conclusion is supported by results showing that both ADP antagonists and ADPase can inhibit the effect of plasmin on platelets. | Adenosine Diphosphate | plasminogen | Homo sapiens |
| 2 | We also demonstrated that pretreatment of platelets with ADP makes the platelets more sensitive to plasmin, and plasmin-induced platelet aggregation is, therefore, observed at lower concentrations where no aggregation occurs in quiescent platelets. | Adenosine Diphosphate | plasminogen | Homo sapiens |
| 3 | In other words, it is thought that ADP potentiates the plasmin-induced aggregation. | Adenosine Diphosphate | plasminogen | Homo sapiens |
| 4 | These data indicate that ADP potentiates plasmin-induced platelet aggregation via the P2T(AC) receptor. | Adenosine Diphosphate | plasminogen | Homo sapiens |
| 5 | In addition, epinephrine, a typical G(i) agonist against platelets, could potentiate the plasmin-induced platelet aggregation, suggesting that the signal via the G(i) protein is involved in potentiating the plasmin-induced platelet aggregation, ADP is secreted from platelet granules, and concomitantly works in conjunction with plasmin in a P2T(AC) receptor-mediated manner. | Adenosine Diphosphate | plasminogen | Homo sapiens |
| 6 | In addition, epinephrine, a typical G(i) agonist against platelets, could potentiate the plasmin-induced platelet aggregation, suggesting that the signal via the G(i) protein is involved in potentiating the plasmin-induced platelet aggregation, ADP is secreted from platelet granules, and concomitantly works in conjunction with plasmin in a P2T(AC) receptor-mediated manner. | Adenosine Diphosphate | plasminogen | Homo sapiens |
| 7 | In addition, epinephrine, a typical G(i) agonist against platelets, could potentiate the plasmin-induced platelet aggregation, suggesting that the signal via the G(i) protein is involved in potentiating the plasmin-induced platelet aggregation, ADP is secreted from platelet granules, and concomitantly works in conjunction with plasmin in a P2T(AC) receptor-mediated manner. | Adenosine Diphosphate | plasminogen | Homo sapiens |