Pub. Date : 2000 Mar
PMID : 10741627
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Prediction of cyclosporine clearance in liver transplant recipients by the use of midazolam as a cytochrome P450 3A probe. | Cyclosporine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | BACKGROUND: Interindividual differences in the kinetics of cyclosporine (INN, ciclosporin) result in part from variations in the activity of cytochrome P450 3A (CYP3A). | Cyclosporine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | BACKGROUND: Interindividual differences in the kinetics of cyclosporine (INN, ciclosporin) result in part from variations in the activity of cytochrome P450 3A (CYP3A). | Cyclosporine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 4 | BACKGROUND: Interindividual differences in the kinetics of cyclosporine (INN, ciclosporin) result in part from variations in the activity of cytochrome P450 3A (CYP3A). | Cyclosporine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 5 | BACKGROUND: Interindividual differences in the kinetics of cyclosporine (INN, ciclosporin) result in part from variations in the activity of cytochrome P450 3A (CYP3A). | Cyclosporine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 6 | The objective of this study was to examine the usefulness of midazolam as a CYP3A probe to predict cyclosporine clearance. | Cyclosporine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 7 | CONCLUSION: Heterogeneity in CYP3A activity contributes to interpatient differences in cyclosporine dosage requirements after liver transplantation. | Cyclosporine | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |