Title : Regulation of thyroid hormones on the production of testosterone in rats.

Pub. Date : 1999 Jun 15

PMID : 10733348






2 Functional Relationships(s)
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1 Thyroidectomy decreased the basal levels of plasma luteinizing hormone (LH) and testosterone, which delayed the maximal response of testosterone to gonadotropin-releasing hormone (GnRH) and hCG in male rats. Testosterone gonadotropin releasing hormone 1 Rattus norvegicus
2 These results suggest that the inhibitory effect of a thyroidectomy on the production of testosterone in rat TICs is in part due to: 1) the decreased basal secretion of pituitary LH and its response to GnRH; 2) the decreased response of TICs to gonadotropin; and 3) the diminished production of cAMP, influx of calcium, and activity of 17beta-HSD. Testosterone gonadotropin releasing hormone 1 Rattus norvegicus