Pub. Date : 1999 Jun 15
PMID : 10733348
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Thyroidectomy decreased the basal levels of plasma luteinizing hormone (LH) and testosterone, which delayed the maximal response of testosterone to gonadotropin-releasing hormone (GnRH) and hCG in male rats. | Testosterone | gonadotropin releasing hormone 1 | Rattus norvegicus |
2 | These results suggest that the inhibitory effect of a thyroidectomy on the production of testosterone in rat TICs is in part due to: 1) the decreased basal secretion of pituitary LH and its response to GnRH; 2) the decreased response of TICs to gonadotropin; and 3) the diminished production of cAMP, influx of calcium, and activity of 17beta-HSD. | Testosterone | gonadotropin releasing hormone 1 | Rattus norvegicus |