Title : Phosphatidylinositol 3-kinase in bovine lens and its stimulation by insulin and IGF-1.

Pub. Date : 2000 Mar

PMID : 10711702






2 Functional Relationships(s)
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Protein Name
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1 Insulin and IGF-1 stimulated the PI-3K activity in epithelial cells in culture by more than 100%, and activation of the enzyme resulted in tyrosine phosphorylation of the p85 subunit. Tyrosine insulin Bos taurus
2 CONCLUSIONS: The activation of PI-3K and its association with specific tyrosine-phosphorylated proteins may be important in insulin and IGF-1 signal transduction in lens epithelial cells. Tyrosine insulin Bos taurus