Pub. Date : 2000 Mar 10
PMID : 10708696
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Systemic administration of the 5-HT(1B) receptor agonist TFMPP attenuated the inhibitory effect of light on pineal melatonin synthesis in a dose-related manner with an apparent ED(50) value of 0.9 mg/kg. | 1-(3-trifluoromethylphenyl)piperazine | 5-hydroxytryptamine receptor 1B | Homo sapiens |
| 2 | The effect of TFMPP on light-induced melatonin suppression was blocked by the 5-HT(1) receptor antagonist, methiothepin, but not by the 5-HT(1A) antagonist, WAY 100,635, consistent with the involvement of 5-HT(1B) receptors. | 1-(3-trifluoromethylphenyl)piperazine | 5-hydroxytryptamine receptor 1B | Homo sapiens |