Title : Effects of CTx and 8-bromo-cAMP on LPS-induced gene expression of cytokines in murine peritoneal macrophages.

Pub. Date : 2000 Mar 16

PMID : 10708595






1 Functional Relationships(s)
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1 Our data clearly demonstrated that in LPS-treated macrophages, cAMP elevator (CTx and 8-bromo-cAMP) could increase IL-1Ra and IL-10 gene expression, while mRNAs of IL-1alpha, IL-12, IL-6, and MIF were decreased and other cytokines like IL-1beta, and IFN-gamma did not give a definite tendency. 8-Bromo Cyclic Adenosine Monophosphate interleukin 6 Mus musculus