Title : Tumour necrosis factor alpha (TNF-alpha) interferes with Fas-mediated apoptotic cell death on rheumatoid arthritis (RA) synovial cells: a possible mechanism of rheumatoid synovial hyperplasia and a clinical benefit of anti-TNF-alpha therapy for RA.

Pub. Date : 2000 Mar

PMID : 10704256






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, removal of TNF-alpha activity by a neutralizing anti-TNF-alpha antibody (cA2) restored Fas-ACD. ammonium ferrous sulfate tumor necrosis factor Homo sapiens
2 Moreover, removal of TNF-alpha activity by a neutralizing anti-TNF-alpha antibody (cA2) restored Fas-ACD. ammonium ferrous sulfate tumor necrosis factor Homo sapiens
3 These results suggest the following: (1) Fas-ACD might be diminished in vivo by local excessive TNF-alpha and this might contribute in part to RASH. ammonium ferrous sulfate tumor necrosis factor Homo sapiens