Title : Cap-dependent deadenylation of mRNA.

Pub. Date : 2000 Mar 1

PMID : 10698948






3 Functional Relationships(s)
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1 Here we report that deadenylation in HeLa cell extracts and by a purified mammalian poly(A)-specific exoribonuclease, PARN (previously designated deadenylating nuclease, DAN), is stimulated by the presence of an m(7)-guanosine cap on substrate RNAs. poly( poly(A)-specific ribonuclease Homo sapiens
2 Here we report that deadenylation in HeLa cell extracts and by a purified mammalian poly(A)-specific exoribonuclease, PARN (previously designated deadenylating nuclease, DAN), is stimulated by the presence of an m(7)-guanosine cap on substrate RNAs. poly( poly(A)-specific ribonuclease Homo sapiens
3 Here we report that deadenylation in HeLa cell extracts and by a purified mammalian poly(A)-specific exoribonuclease, PARN (previously designated deadenylating nuclease, DAN), is stimulated by the presence of an m(7)-guanosine cap on substrate RNAs. poly( poly(A)-specific ribonuclease Homo sapiens