Title : Both low and high concentrations of staurosporine induce G1 arrest through down-regulation of cyclin E and cdk2 expression.

Pub. Date : 1999 Dec

PMID : 10698260






1 Functional Relationships(s)
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1 Moreover, 200 nM staurosporine increased the expression of p53 and p21 proteins and inhibited the expression of cyclin E and cdk2 proteins, suggesting that the cells were arrested in the G1 phase of the next cycle. Staurosporine tumor protein p53 Homo sapiens