Title : Effects of long-term administration of UFT plus leucovorin on colorectal tumors induced with 1,2-dimethylhydrazine in rats.

Pub. Date : 1999 Nov-Dec

PMID : 10697523






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Thirty-week administration of UFT with or without leucovorin markedly suppressed both colorectal carcinogenesis and tumor growth, resulted in the increase of thymidylate synthase inhibition and the decrease of thymidine kinase activity in the tumor cells. Tegafur thymidylate synthetase Rattus norvegicus