Title : Impaired relaxation of stomach smooth muscle in mice lacking cyclic GMP-dependent protein kinase I.

Pub. Date : 2000 Jan

PMID : 10694248






1 Functional Relationships(s)
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1 The responses to the NO donor, SIN-1 (10 nM - 100 microM), and to 8-Br-cyclic GMP (10 nM - 100 microM) were markedly impaired in strips from cGKI-deficient mice, whereas the responses to VIP (0.1 nM - 1 microM) and forskolin (0.1 nM - 1 microM) were similar to those in wild type mice. Colforsin protein kinase cGMP-dependent 1 Homo sapiens