Title : p53 gene mutation, tumor p53 protein overexpression, and serum p53 autoantibody generation in patients with breast cancer.

Pub. Date : 2000 Feb

PMID : 10693987






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Four of the five mutations in the p53 antibody-positive patients affected a Tyr residue, whereas none of the gene abnormalities in the seronegative patients had such an effect. Tyrosine tumor protein p53 Homo sapiens
2 Further, p53 antibody-positive patients do not have higher frequency of p53 gene mutations than p53 antibody-negative patients, but the former patient group is associated with a Tyr substitution in the protein product. Tyrosine tumor protein p53 Homo sapiens