Title : Prevention of endotoxin-induced lethality in mice by calmodulin kinase activator.

Pub. Date : 2000 Mar

PMID : 10683464






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Porphyromonas gingivalis strain 381 lipid A showed lower activity in inducing interleukin (IL)-1alpha and IL-1beta production and cytokine mRNA expression than synthetic Escherichia coli lipid A (compound 506) in alveolar macrophages of C57BL/6 mice. Lipid A interleukin 1 beta Mus musculus
2 A calmodulin (CaM) antagonist, W-7, inhibited IL-1beta production and its mRNA expression induced by P. gingivalis lipid A but not compound 506 in alveolar macrophages. Lipid A interleukin 1 beta Mus musculus