Title : Cytochrome P450 metabolites of arachidonic acid may be important mediators in angiotensin II-induced vasoconstriction in the rat mesentery in vivo.

Pub. Date : 2000 Mar

PMID : 10677385






2 Functional Relationships(s)
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1 The results from the present studies combined with the existing evidence that angiotensin II stimulates the release of 20-HETE, a CYP-450 metabolite of arachidonic acid, suggest that CYP-450-derived HETEs may be important mediators in angiotensin II-induced vasoconstriction. Hydroxyeicosatetraenoic Acids angiotensinogen Rattus norvegicus
2 The results from the present studies combined with the existing evidence that angiotensin II stimulates the release of 20-HETE, a CYP-450 metabolite of arachidonic acid, suggest that CYP-450-derived HETEs may be important mediators in angiotensin II-induced vasoconstriction. Hydroxyeicosatetraenoic Acids angiotensinogen Rattus norvegicus