Pub. Date : 2000 Feb
PMID : 10672042
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: 20alpha-Hydroxysteroid dehydrogenase (HSD) is a member of the aldo-keto reductase (AKR) superfamily and catalyses the reaction of progesterone to the inactive form 20alpha-hydroxyprogesterone. | Progesterone | aldo-keto reductase family 1 member C1 | Homo sapiens |
| 2 | BACKGROUND: 20alpha-Hydroxysteroid dehydrogenase (HSD) is a member of the aldo-keto reductase (AKR) superfamily and catalyses the reaction of progesterone to the inactive form 20alpha-hydroxyprogesterone. | Progesterone | aldo-keto reductase family 1 member C1 | Homo sapiens |
| 3 | The induction of 20alpha-HSD is thought to be responsible for the decrease in plasma progesterone at term. | Progesterone | aldo-keto reductase family 1 member C1 | Homo sapiens |
| 4 | CONCLUSION: The human gene encoding for the progesterone-metabolizing enzyme 20alpha-HSD in the female reproductive system was cloned, and its expression and gene localization were elucidated. | Progesterone | aldo-keto reductase family 1 member C1 | Homo sapiens |