Title : Resveratrol inhibits cyclooxygenase-2 transcription in human mammary epithelial cells.

Pub. Date : 1999

PMID : 10668496






2 Functional Relationships(s)
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1 In this study, we investigated whether resveratrol, a chemopreventive agent found in grapes, could suppress phorbol ester (PMA)-mediated induction of COX-2 in human mammary and oral epithelial cells. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens
2 Nuclear runoffs revealed increased rates of COX-2 transcription after treatment with PMA, an effect that was inhibited by resveratrol. Tetradecanoylphorbol Acetate prostaglandin-endoperoxide synthase 2 Homo sapiens