Title : Interaction of docetaxel ("Taxotere") with human P-glycoprotein.

Pub. Date : 1999 Dec

PMID : 10665657






1 Functional Relationships(s)
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1 The inhibition of [14C]docetaxel transport by the MDR modulators, as well as daunorubicin and vinblastine, was also found in LLC-PK1 cells, which endogenously express P-gp at lower levels, and concentrations showing similar levels of inhibition were lower than those in the case of LLC-GA5-COL150 cells. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens