Title : Inhibition of bradykinin-induced phosphoinositide hydrolysis and Ca2+ mobilisation by phorbol ester in rat cultured vascular smooth muscle cells.

Pub. Date : 1999 Dec

PMID : 10659998






2 Functional Relationships(s)
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1 Prior treatment of VSMCs with staurosporine (1 microM), a PKC inhibitor, inhibited the ability of PMA to attenuate BK-induced responses, suggesting that the inhibitory effect of PMA is mediated through the activation of PKC. Tetradecanoylphorbol Acetate protein kinase C, alpha Rattus norvegicus
2 Prior treatment of VSMCs with staurosporine (1 microM), a PKC inhibitor, inhibited the ability of PMA to attenuate BK-induced responses, suggesting that the inhibitory effect of PMA is mediated through the activation of PKC. Tetradecanoylphorbol Acetate protein kinase C, alpha Rattus norvegicus