Title : Drug-induced apoptosis in lung cnacer cells is not mediated by the Fas/FasL (CD95/APO1) signaling pathway.

Pub. Date : 2000 Jan

PMID : 10656451






1 Functional Relationships(s)
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1 In the present work, the involvement of the Fas/FasL system in drug-induced apoptosis in lung cancer cells was investigated upon exposure to four cytotoxic drugs (cisplatin, gemcitabine, topotecan, and paclitaxel). Topotecan Fas ligand Homo sapiens