Title : Effects of sildenafil on cAMP and cGMP levels in isolated human cavernous and cardiac tissue.

Pub. Date : 2000 Jan

PMID : 10654914






1 Functional Relationships(s)
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1 OBJECTIVES: To further investigate the mechanism of action of sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase 5 (PDE5), that has been proved to be effective in the treatment of male erectile dysfunction. Sildenafil Citrate phosphodiesterase 5A Homo sapiens