Title : Efficacy of N-acetylcysteine and all-trans retinoic acid in restoring in vitro effective hemopoiesis in myelodysplastic syndromes.

Pub. Date : 2000 Feb

PMID : 10654448






4 Functional Relationships(s)
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1 We evaluated the in vitro effect on clonogenic potential (CFU-GM) and apoptosis in myelodysplastic syndromes (MDS) progenitors of an anti-oxidant (N-acetylcysteine, NAC) and/or a differentiating (all-trans retinoic acid, ATRA) agent. Tretinoin synuclein alpha Homo sapiens
2 We evaluated the in vitro effect on clonogenic potential (CFU-GM) and apoptosis in myelodysplastic syndromes (MDS) progenitors of an anti-oxidant (N-acetylcysteine, NAC) and/or a differentiating (all-trans retinoic acid, ATRA) agent. Tretinoin synuclein alpha Homo sapiens
3 NAC + ATRA conferred a significant advantage in terms of CFU-GM with respect to NAC and ATRA alone. Tretinoin synuclein alpha Homo sapiens
4 NAC + ATRA conferred a significant advantage in terms of CFU-GM with respect to NAC and ATRA alone. Tretinoin synuclein alpha Homo sapiens