Title : Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds.

Pub. Date : 1999 Dec

PMID : 10647906






1 Functional Relationships(s)
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1 Regarding ethoxyresorufin O-deethylation catalysed by CYP1A1 and benzyloxyresorufin O-dealkylation by CYP2B6, the subtle change of a substitution of the 1,4-benzothiazine structure affected the inhibition selectivity. ethoxyresorufin cytochrome P450 family 1 subfamily A member 1 Homo sapiens