Title : A protein kinase from neutrophils that specifically recognizes Ser-3 in cofilin.

Pub. Date : 2000 Jan 28

PMID : 10644754






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 A protein kinase from neutrophils that specifically recognizes Ser-3 in cofilin. Serine cofilin 1 Homo sapiens
2 Phosphorylation of cofilin on serine residue 3 is known to block these activities. Serine cofilin 1 Homo sapiens
3 We now report that neutrophils contain a protein kinase that selectively catalyzes the phosphorylation of cofilin on serine 3 (>/=70%) and a nonspecific kinase that recognizes multiple sites in this protein. Serine cofilin 1 Homo sapiens
4 Thus, neutrophils contain a protein kinase distinct from LIM kinase-1/2 that selectively recognizes serine 3 in cofilin. Serine cofilin 1 Homo sapiens