Title : Contribution of NK(2) tachykinin receptors to propulsion in the rabbit distal colon.

Pub. Date : 2000 Jan

PMID : 10644572






1 Functional Relationships(s)
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1 Experiments on colonic circular muscle strips showed that contractile responses to [beta-Ala(8)]NKA-(4-10) (1 nM-1 microM), a selective NK(2)-receptor agonist, were competitively antagonized by MEN-10627 (1-100 nM), whereas SR-48968 (0.1-10 nM) caused an insurmountable antagonism, thus confirming the difference in the mode of action of the two compounds. beta-Alanine tachykinin receptor 2 Homo sapiens