Title : Subpressor doses of angiotensin II increase plasma F(2)-isoprostanes in rats.

Pub. Date : 2000 Jan

PMID : 10642344






2 Functional Relationships(s)
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1 The present study was performed to determine whether physiologically relevant doses of angiotensin II (Ang II), which do not affect renal hemodynamics but do cause slow response hypertension, result in oxidative stress as measured by production of vasoconstrictor F(2)-isoprostane, a prostaglandin-like non-cyclooxygenase-produced arachidonic acid metabolite that is the end product of lipid peroxidation. Prostaglandins angiotensinogen Rattus norvegicus
2 The present study was performed to determine whether physiologically relevant doses of angiotensin II (Ang II), which do not affect renal hemodynamics but do cause slow response hypertension, result in oxidative stress as measured by production of vasoconstrictor F(2)-isoprostane, a prostaglandin-like non-cyclooxygenase-produced arachidonic acid metabolite that is the end product of lipid peroxidation. Prostaglandins angiotensinogen Rattus norvegicus