Title : Mannosamine inhibits aggrecanase-mediated changes in the physical properties and biochemical composition of articular cartilage.

Pub. Date : 2000 Feb 1

PMID : 10640399






1 Functional Relationships(s)
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1 Recent studies have demonstrated that the hexosamines glucosamine (GlcN) and mannosamine (ManN) can inhibit aggrecanase-mediated cleavage of aggrecan in IL-1-treated cartilage cultures. Hexosamines interleukin 1 alpha Homo sapiens