Pub. Date : 1999 Dec
PMID : 10639016
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Since aspirin is a weak inhibitor of the inducible isoform of prostaglandin H synthase (COX-2), it was suggested that COX-2 may play a role in aspirin resistance. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
2 | Since aspirin is a weak inhibitor of the inducible isoform of prostaglandin H synthase (COX-2), it was suggested that COX-2 may play a role in aspirin resistance. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
3 | Since aspirin is a weak inhibitor of the inducible isoform of prostaglandin H synthase (COX-2), it was suggested that COX-2 may play a role in aspirin resistance. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
4 | Since aspirin is a weak inhibitor of the inducible isoform of prostaglandin H synthase (COX-2), it was suggested that COX-2 may play a role in aspirin resistance. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
5 | However the cellular source(s) of COX-2 possibly responsible for aspirin resistance remains unknown. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
6 | Our results argue against the involvement of COX-2 in TX biosynthesis by activated platelets and consequently dispute platelet COX-2 expression as an important mechanism of aspirin resistance. | Aspirin | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |