Title : Molecular modelling and QSAR of reversible acetylcholines-terase inhibitors.

Pub. Date : 2000 Mar

PMID : 10637365






1 Functional Relationships(s)
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1 These data are summarised from nearly all therapeutically important chemical classes of reversible AChE inhibitors, e.g., derivatives of physostigmine, tacrine, donepezil and huperzine A. Interactions observed from X-ray crystallography between these inhibitors and AChE have also been incorporated and compared with modelling and QSAR results. Physostigmine acetylcholinesterase (Cartwright blood group) Homo sapiens