Title : Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus.

Pub. Date : 2000 Jan

PMID : 10633490






1 Functional Relationships(s)
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1 Coadministration of rolipram or Ro 20-1724 with an antidepressant (either desipramine or Org 4428) for 21 d resulted in a significant induction of BDNF mRNA in hippocampus relative to administration of vehicle. Desipramine brain-derived neurotrophic factor Rattus norvegicus