Title : Involvement of resident macrophages and mast cells in the writhing nociceptive response induced by zymosan and acetic acid in mice.

Pub. Date : 2000 Jan 3

PMID : 10633169






2 Functional Relationships(s)
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1 These cells modulate the nociceptive response induced by zymosan and acetic acid via release of tumour necrosis factor alpha (TNF-alpha), interleukin 1beta and interleukin 8. Zymosan interleukin 1 beta Mus musculus
2 In conclusion, our results suggest that the nociceptive activity of zymosan and acetic acid in the writhing model is due to the release of TNF-alpha, interleukin 1beta and interleukin 8 by resident peritoneal macrophages and mast cells. Zymosan interleukin 1 beta Mus musculus