Pub. Date : 1999 Dec 20
PMID : 10630412
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Trypsin digestion of steroid-free, but not steroid-bound, rat glucocorticoid receptor (GR) has recently been reported to occur at arginine-651 (R651). | Steroids | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |
| 2 | This hypothesis is supported by the current model of the GR ligand binding domain (LBD), which is based on the X-ray structures of several related receptor LBDs and places R651 in the middle of the putative alpha-helix 6 (649-EQRMS-653 of rat GR), close to the bound steroid. | Steroids | nuclear receptor subfamily 3, group C, member 1 | Rattus norvegicus |